Atrioventricular Valve Failure in Fontan Palliation

G King; J Ayer; D Celermajer; D Zentner; R Justo; P Disney; D Zannino; Y d'Udekem

Journal article

Atrioventricular Valve Failure in Fontan Palliation

G King, J Ayer, D Celermajer, D Zentner, R Justo, P Disney, D Zannino, Y d'Udekem

Journal of the American College of Cardiology | ELSEVIER SCIENCE INC | Published : 2019

DOI: 10.1016/j.jacc.2018.12.025

Abstract

Background: Atrioventricular valve failure (moderate or greater regurgitation, or valve operation) is a risk factor for adverse outcomes in patients undergoing Fontan palliation. Objectives: This study determined the incidence of atrioventricular valve failure and its clinical impact on patients undergoing Fontan palliation. Methods: A retrospective cohort longitudinal study was conducted using patient data extracted from an existing bi-national, population-based registry. Results: A total of 1,468 patients who underwent Fontan palliation were identified; complete follow-up data were available for 1,199 patients. Six hundred eighty-six patients had 2 atrioventricular valves, 286 had a single..

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University of Melbourne Researchers

Dominica Zentner Author

Diana Zannino Author

Yves D'Udekem D'Acoz Author

Related Projects (1)

GIVING AN ADULT LIFE AFTER FONTAN SURGERY TO THOSE WITH THE MOST SEVERE CONGENITAL HEART CONDITIONS

The Fontan operation is the last of a series of operations performed for babies born with a single pumping heart chamber (ventricle). In the..

Grants

Funding Acknowledgements

This work was supported by a National Health and Medical Research Council (NHMRC) Partnership grant (1076849). Dr. King is supported by an Avant Doctor in Training Research Scholarship. Dr. d'Udekem has been a consultant for Merck Sharp and Dohme and Actelion. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.